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BIO:ON Insight #20 · Oct 13, 2026

Who pays first changes everything

Ono pays $80M upfront for Biohaven's IgG degraders with Japan, Korea and ASEAN rights, a Cochrane review links pharma perks to costlier prescribing, and hospitals sue to stop 340B rebates. This week's question: who pays first, and who gets paid later?

BD, licensing & M&AImmunology, rare & infectiousMarket access & pricing한국어판 보기

What I learned this week

What stuck with me after all three was the order, not the amounts. The same money carries different risk and different leverage depending on whether it goes first or arrives later. Next time you meet a big number, ask "who pays this, when, and on what conditions?" The headline gets much clearer. See you next issue. 🙏

Yaehyun Lee · Quoted from the Editor's Insight I wrote for this issue.

Stories in this issue

  1. Pipeline Analysis

    Ono pays $80M upfront for Japan, Korea and ASEAN rights to Biohaven's IgG degraders

    Ono PharmaceuticalBiohavenBHV-1300

  2. Market Trends

    Cochrane review links pharma perks to costlier, less appropriate prescribing

  3. Market Trends

    US hospitals sue to halt the 340B rebate pilot before its January start

    US HHS / HRSA

AI summary

  1. 1Ono is paying Biohaven $80M upfront for Japan, Korea, Taiwan and ASEAN rights to three IgG degraders, led by Phase 3 Graves' candidate BHV-1300.
  2. 2A Cochrane review of 93 studies concluded that pharma payments and gifts increase inappropriate prescribing and probably raise costs.
  3. 3US hospitals sued to block the 340B rebate pilot, which would swap upfront discounts for rebates on 21 drugs from January 1.

Relevant rolesBDSales & marketingMarket access

Summary and tags generated by AI from the issue text.

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