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BIO:ON Insight #7 · Jul 6, 2026

Fill the pipeline with AI, fend off generics, buy your way out: surviving the patent cliff

Takeda signs a $600M AI deal with Insilico, generic makers challenge Lilly's tirzepatide patents, and AbbVie buys Apogee for $10.9B. Three ways Big Pharma tries to survive the patent cliff.

AI drug discoveryBD, licensing & M&AObesity & metabolic한국어판 보기

What I learned this week

This week's three stories look different, but they read as one formula. As the patent cliff gets closer, Big Pharma reaches for AI, the courts, M&A, or all three at once. That matters beyond corporate strategy: the strategy a company picks decides which skills the market needs, and so the shape of the opportunities open to you. See you next issue. 🙏

Yaehyun Lee · Quoted from the Editor's Insight I wrote for this issue.

Stories in this issue

  1. Pipeline Analysis

    Takeda × Insilico: $600M AI drug discovery partnership

    TakedaInsilico Medicine

  2. Market Trends

    Generic makers challenge Lilly's tirzepatide patents

    Eli Lillytirzepatide

  3. Pipeline Analysis

    AbbVie to acquire Apogee Therapeutics for $10.9B

    AbbVieApogee Therapeutics

AI summary

  1. 1Takeda signed a $600M AI drug discovery deal with Insilico Medicine to help fill its patent cliff.
  2. 2Generic makers filed suits to invalidate Zepbound (tirzepatide) patents.
  3. 3AbbVie is acquiring Apogee Therapeutics for $10.9B, widening its atopic dermatitis and asthma franchise.

Relevant rolesBDInvestment & IRRegulatory affairs

Summary and tags generated by AI from the issue text.

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